ELISA EYA4 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:CMD1J antibody; Deafness, autosomal dominant 10 antibody; DFNA 10 antibody; DFNA10 antibody; dJ78N10.1 (eyes absent (Drosophila) homolog 4) antibody; dJ78N10.1 (eyes absent) antibody; EYA 4 antibody; eya4 antibody; EYA4_ antibody; Eyes absent 4 antibody; Eyes absent homolog 4 (Drosophila) antibody; Eyes absent homolog 4 antibody; HGNC:3522 antibody; OTTHUMP00000040267 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O95677 Immunogen:Recombinant Eyes absent homolog 4 protein (153-224AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Tyrosine phosphatase that specifically dephosphorylates \'Tyr-142\' of histone H2AX (H2AXY142ph). \'Tyr-142\' phosphorylation of histone H2AX plays a central role in DNA repair and acts as a mark that distinguishes between apoptotic and repair responses to genotoxic stress. Promotes efficient DNA repair by dephosphorylating H2AX, promoting the recruitment of DNA repair complexes containing MDC1. Its function as histone phosphatase probably explains its role in transcription regµLation during organogenesis. May be involved in development of the eye (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EYA4 Research Areas:Epigenetics and Nuclear Signaling; Neuroscience; CardiovascµLar