ELISA Gzma Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Gzma antibody; Ctla-3 antibody; Ctla3 antibody; Mtsp-1 antibody; Granzyme A antibody; EC 3.4.21.78 antibody; Autocrine thymic lymphoma granzyme-like serine protease antibody; CTLA-3 antibody; Fragmentin-1 antibody; T cell-specific serine protease 1 antibody; TSP-1 antibody Product Type:Polyclonal Antibody Immunogen Species:Mus muscµLus (Mouse) UniProt ID:P11032 Immunogen:Recombinant Mouse Granzyme A protein (29-260AA) Raised in:Rabbit Reactivity:Mouse Tested Applications:ELISA Background:Abundant protease in the cytosolic granµLes of cytotoxic T-cells and NK-cells which activates caspase-independent cell death with morphological features of apoptosis when delivered into the target cell throµgh the immunological synapse. It cleaves after Lys or Arg. Cleaves APEX1 after 'Lys-31' and destroys its oxidative repair activity. Cleaves the nucleosome assembly protein SET after 'Lys-189', which disrupts its nucleosome assembly activity and allows the SET complex to translocate into the nucleus to nick and degrade the DNA (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:Gzma Research Areas:Others