ELISA H2AFB1 anti-

Quantity :50µg Clone Number: Aliases:H2AB1 antibody; H2AFB1 antibody; Histone H2A-Bbd type 1 antibody; H2A Barr body-deficient antibody; H2A.B antibody; H2A.Bbd antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P0C5Y9 Immunogen:Recombinant Histone H2A-Bbd type 1 protein (1-115AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA, IHC, IF; Recommended dilution: IHC:1:20-1:200, IF:1:50-1:200 Background:Atypical histone H2A which can replace conventional H2A in some nucleosomes and is associated with active transcription and mRNA processing. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellµLar machineries which require DNA as a template. Histones thereby play a central role in transcription regµLation, DNA repair, DNA replication and chromosomal stability. Nucleosomes containing this histone are less rigid and organize less DNA than canonical nucleosomes in vivo. They are enriched in actively transcribed genes and associate with the elongating form of RNA polymerase. They associate with spliceosome components and are required for mRNA splicing. May participate in spermatogenesis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Non-conjµgated Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:H2AFB1 Research Areas:Epigenetics and Nuclear Signaling