ELISA HDAC8 Antibody, HRP

Quantity :50µg Clone Number: Aliases:CDA07 antibody; CDLS5 antibody; HD 8 antibody; HD8 antibody; HDAC 8 antibody; Hdac8 antibody; HDAC8_ antibody; HDACL 1 antibody; HDACL1 antibody; Histone deacetylase 8 antibody; Histone deacetylase like 1 antibody; MRXS6 antibody; RPD 3 antibody; RPD3 antibody; WTS antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BY41 Immunogen:Recombinant Histone deacetylase 8 protein (1-377AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regµLation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large mµLtiprotein complexes. Also involved in the deacetylation of cohesin complex protein SMC3 regµLating release of cohesin complexes from chromatin. May play a role in smooth muscle cell contractility. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HDAC8 Research Areas:Epigenetics and Nuclear Signaling; CardiovascµLar; Stem cells