ELISA H2AFV Antibody, Biotin

Quantity :50µg Clone Number: Aliases:H2AFV antibody; H2AV antibody; Histone H2A.V antibody; H2A.F/Z antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q71UI9 Immunogen:Recombinant Histone H2A.V protein (1-128AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Variant histone H2A which replaces conventional H2A in a subset of nucleosomes. Nucleosomes wrap and compact DNA into chromatin, limiting DNA accessibility to the cellµLar machineries which require DNA as a template. Histones thereby play a central role in transcription regµLation, DNA repair, DNA replication and chromosomal stability. DNA accessibility is regµLated via a complex set of post-translational modifications of histones, also called histone code, and nucleosome remodeling. May be involved in the formation of constitutive heterochromatin. May be required for chromosome segregation during cell division. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:H2AFV Research Areas:Others