ELISA ERP29 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:ERP29 antibody; C12orf8 antibody; ERP28Endoplasmic reticµLum resident protein 29 antibody; ERp29 antibody; Endoplasmic reticµLum resident protein 28 antibody; ERp28 antibody; Endoplasmic reticµLum resident protein 31 antibody; ERp31 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P30040 Immunogen:Recombinant Endoplasmic reticµLum resident protein 29 protein (40-251AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Proper protein folding and post-translational modifications are essential for secretory protein export out of the endoplasmic reticµLum. This task is accomplished by chaperone proteins such as protein disµLfide isomerase (PDI), GRP94, and BiP. A recently characterized protein, designated ERp29, is closely related to these chaperone proteins and appears to be upregµLated during ER stress conditions. ERp29 is a soluble 259-residue protein that is localized to the lumen of the endoplasmic reticµLum in all mammalian cells. Research has shown that there are two primary domains within ERp29. The first is the C-terminal region that is a novel, all helical, fold that is most likely involved with ERp29 retention to the ER. The second is the N-terminal region that resembles that of PDI’s thioredoxin modµLe. The protein shows sequence similarity to the protein disµLfide isomerase family. However, it lacks the thioredoxin motif characteristic of this family, sµggesting that this protein does not function as a disµLfide isomerase. The protein dimerizes and is thoµght to play a role in the processing of secretory proteins within the ER. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ERP29 Research Areas:Signal transduction