ELISA HDAC4 (Ab-632) anti-

Quantity :100µL Clone Number: Aliases:AHO3 antibody; BDMR antibody; EC 3.5.1.98 antibody; HA6116 antibody; HD 4 antibody; HD4 antibody; HDAC 4 antibody; HDAC A antibody; HDAC4 antibody; HDAC4_ antibody; HDACA antibody; Histone deacetylase 4 antibody; Histone Deacetylase A antibody; KIAA0288 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:P56524 Immunogen:Peptide sequence around aa. 630~634 (A-Q-S-S-P) derived from HDAC4. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB, IF; WB:1:500-1:1000, IF:1:100-1:200 Background:Responsible for the deacetylation of lysine residues on the N-terminal part of the core histones (H2A, H2B, H3 and H4). Histone deacetylation gives a tag for epigenetic repression and plays an important role in transcriptional regµLation, cell cycle progression and developmental events. Histone deacetylases act via the formation of large mµLtiprotein complexes. Involved in muscle maturation via its interaction with the myocyte enhancer factors such as MEF2A, MEF2C and MEF2D. Wang AH, et al. (2000) Mol Cell Biol. 20(18): 6904-6912. Grozinger CM, et al. (2000) Proc Natl Acad Sci U S A. 97(14): 7835-7840. Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HDAC4 Research Areas:Epigenetics and Nuclear Signaling;CardiovascµLar;Stem cells