ELISA DHRS2 anti-

Quantity :100µL Clone Number: Aliases:DHRS2 antibody; SDR25C1 antibody; Dehydrogenase/reductase SDR family member 2 antibody; mitochondrial antibody; EC 1.1.1.- antibody; Dicarbonyl reductase HEP27 antibody; Protein D antibody; Short chain dehydrogenase/reductase family 25C member 1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q13268 Immunogen:SyntheQuantityd peptide derived from internal of DHRS2. Raised in:Rabbit Reactivity: Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Displays NADPH-dependent dicarbonyl reductase activity in vitro with 3,4-Hexanedione, 2,3-Heptanedione and 1-Phenyl-1,2-propanedione as substrates. No reductase activity is displayed in vitro with steroids, retinoids and sµgars as substrates. Attenuates MDM2-mediated p53/TP53 degradation, leading to p53/TP53 stabilization and increased transcription activity, resµLting in the accumµLation of MDM2 and CDKN1A/p21. Gabrielli F., Eur. J. Biochem. 232:473-477(1995). Pellegrini S., Biochim. Biophys. Acta 1574:215-222(2002). Suzuki Y., Submitted (APR-2005) to the EMBL/GenBank/DDBJ databases. Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:DHRS2 Research Areas:Cancer;Metabolism;Signal transduction