ELISA HA Antibody, Biotin

Quantity :50µg Clone Number: Aliases:HA antibody; Hemagglutinin [Cleaved into: Hemagglutinin HA1 chain; Hemagglutinin HA2 chain] antibody Product Type:Polyclonal Antibody Immunogen Species:Influenza A virus (strain A/Hickox/1940 H1N1) UniProt ID:Q0HD60 Immunogen:Recombinant Influenza A virus Hemagglutinin protein (18-343AA) Raised in:Rabbit Reactivity:Influenza A virus Tested Applications:ELISA Background:Binds to sialic acid-containing receptors on the cell surface, bringing about the attachment of the virus particle to the cell. This attachment induces virion internalization of about two third of the virus particles throµgh clathrin-dependent endocytosis and about one third throµgh a clathrin- and caveolin-independent pathway. Plays a major role in the determination of host range restriction and virµLence. Class I viral fusion protein. Responsible for penetration of the virus into the cell cytoplasm by mediating the fusion of the membrane of the endocytosed virus particle with the endosomal membrane. Low pH in endosomes induces an irreversible conformational change in HA2, releasing the fusion hydrophobic peptide. Several trimers are required to form a competent fusion pore (By similarity). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HA Research Areas:Others