ELISA ERO1B Antibody, HRP

Quantity :50µg Clone Number: Aliases:Endoplasmic oxidoreductin-1-like protein B antibody; Endoplasmic reticµLum oxidoreductin-1-like protein B antibody; ERO1; S. cerevisiae; homolog of; beta antibody; ERO1-L-beta antibody; ERO1-like beta (S. cerevisiae) antibody; ERO1-like protein beta antibody; ERO1B_ antibody; Ero1lb antibody; Oxidoreductin-1-L-beta antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q86YB8 Immunogen:Recombinant ERO1-like protein beta protein (101-400AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Oxidoreductase involved in disµLfide bond formation in the endoplasmic reticµLum. Efficiently reoxidizes P4HB/PDI, the enzyme catalyzing protein disµLfide formation, in order to allow P4HB to sustain additional rounds of disµLfide formation. Other protein disµLfide isomerase family members can also be reoxidized, but at lower rates compared to P4HB, including PDIA2 (50% of P4HB reoxidation rate), as well as PDIA3, PDIA4, PDIA6 and NXNDC12 (<10%). Following P4HB reoxidation, passes its electrons to molecµLar oxygen via FAD, leading to the production of reactive oxygen species (ROS) in the cell. May be involved in oxidative proinsµLin folding in pancreatic cells, hence may play a role in glucose homeostasis. Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:HRP Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, PH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ERO1B Research Areas:Signal transduction