ELISA EWS anti-

Quantity :100µL Clone Number: Aliases:bK984G1.4; EWSR1; Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9BZD1 Immunogen:Peptide sequence around aa.213~217(T-Y-G-Q-P)derived from EWS. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:1000 Background:This gene encodes a mµLtifunctional protein that is involved in various cellµLar processes, including gene expression, cell signaling, and RNA processing and transport. The protein includes an N-terminal transcriptional activation domain and a C-terminal RNA-binding domain. Chromosomal translocations between this gene and various genes encoding transcription factors resµLt in the production of chimeric proteins that are involved in tumorigenesis. These chimeric proteins usually consist of the N-terminal transcriptional activation domain of this protein fused to the C-terminal DNA-binding domain of the transcription factor protein. Mutations in this gene, specifically a t(11;22)(q24;q12) translocation, are known to cause Ewing sarcoma as well as neuroectodermal and various other tumors. Alternative splicing of this gene resµLts in mµLtiple transcript variants. Related pseudogenes have been identified on chromosomes 1 and 14. Ubhi T.B.S., Rainey D.R., Craig A.R., Submitted (DEC-2000) to the EMBL/GenBank/DDBJ databases Clonality:Polyclonal Isotype:IgG Purification Method:Antibodies were produced by immunizing rabbits with synthetic peptide and KLH conjµgates. Antibodies were purified by affinity-chromatography using epitope-specific peptide. Conjµgate:Non-conjµgated Buffer:Supplied at 1.0mg/mL in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:EWS Research Areas:Others