ELISA HEY1 Antibody, Biotin

Quantity :50µg Clone Number: Aliases:Basic helix loop helix protein OAF1 antibody; bHLHb31 antibody; CardiovascµLar helix loop-helix factor 2 antibody; CardiovascµLar helix-loop-helix factor 2 antibody; CHF-2 antibody; CHF2 antibody; Class B basic helix-loop-helix protein 31 antibody; Hairy and enhancer of split related protein 1 antibody; Hairy and enhancer of split-related protein 1 antibody; Hairy enhancer-of-split related with YRPW motif protein 1 antibody; Hairy related transcription factor 1 antibody; Hairy-related transcription factor 1 antibody; Hairy/enhancer of split related with YRPW motif 1 antibody; Hairy/enhancer-of-split related with YRPW motif protein 1 antibody; HERP2 antibody; HES related repressor protein 1 antibody; HES-related repressor protein 1 antibody; HES-related repressor protein 2 antibody; HESR-1 antibody; HESR1 antibody; HEY 1 antibody; hey1 antibody; HEY1_ antibody; hHRT1 antibody; HRT-1 antibody; HRT1 antibody; OAF1 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9Y5J3 Immunogen:Recombinant Hairy/enhancer-of-split related with YRPW motif protein 1 protein (200-300AA) Raised in:Rabbit Reactivity: Tested Applications:ELISA Background:Transcriptional repressor which binds preferentially to the canonical E box sequence 5\'-CACGTG-3\' (PubMed:11095750). Downstream effector of Notch signaling required for cardiovascµLar development. Specifically required for the Notch-induced endocardial epithelial to mesenchymal transition, which is itself criticial for cardiac valve and septum development. May be required in conjunction with HEY2 to specify arterial cell fate or identity. Promotes maintenance of neuronal precursor cells and glial versus neuronal fate specification. Represses transcription by the cardiac transcriptional activators GATA4 and GATA6 and by the neuronal bHLH factors ASCL1/MASH1 and NEUROD4/MATH3 (PubMed:15485867). Involved in the regµLation of liver cancer cells self-renewal (PubMed:25985737). Clonality:Polyclonal Isotype:IgG Purification Method:>95%, Protein G purified Conjµgate:Biotin Buffer:Preservative: 0.03% Proclin 300 Constituents: 50% Glycerol, 0.01M PBS, pH 7.4 Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HEY1 Research Areas:Epigenetics and Nuclear Signaling; CardiovascµLar