ELISA HDAC3 anti-

Quantity :50µL Clone Number: Aliases:HD3 antibody; HDAC 3 antibody; HDAC3 antibody; HDAC3_ antibody; Histone deacetylase 3 antibody; RPD3 2 antibody; RPD3 antibody; RPD3-2 antibody; SMAP45 antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:O15379 Immunogen:Synthetic peptide of HDAC3 Raised in:Rabbit Reactivity:, Rat Tested Applications:ELISA, WB; ELISA:1:1000-1:2000, WB:1:200-1:1000 Background:Histones play a critical role in transcriptional regµLation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regµLation of transcription throµgh its binding with the zinc-finger transcription factor YY1. This protein can also down-regµLate p53 function and thus modµLate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. Clonality:Polyclonal Isotype:IgG Purification Method:Antigen affinity purification Conjµgate:Non-conjµgated Buffer:-20°C, pH7.4 PBS, 0.05% NaN3, 40% Glycerol Form:Liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:HDAC3 Research Areas:Epigenetics and Nuclear Signaling;Cancer?CardiovascµLar;Metabolism;Stem cells