ELISA ERAP1 anti-

Quantity :100µL Clone Number: Aliases:A LAP antibody; A-LAP antibody; Adipocyte derived leucine aminopeptidase antibody; Adipocyte-derived leucine aminopeptidase antibody; ALAP antibody; Aminopeptidase PILS antibody; Aminopeptidase regµLator of TNFR1 shedding antibody; APPILS antibody; ARTS 1 antibody; ARTS-1 antibody; Arts1 antibody; Endoplasmic reticµLum aminopeptidase 1 antibody; Endoplasmic reticµLum aminopeptidase associated with antigen processing antibody; ERAAP antibody; ERAAP1 antibody; ERAP 1 antibody; Erap1 antibody; ERAP1_ antibody; KIAA0525 antibody; kiaa0525 protein antibody; PILS AP antibody; PILS-AP antibody; PILSA antibody; PILSAP antibody; Puromycin insensitive leucyl specific aminopeptidase antibody; Puromycin-insensitive leucyl-specific aminopeptidase antibody; Type 1 tumor necrosis factor receptor shedding aminopeptidase regµLator antibody; type 1 tumor necrosis factor receptors shedding aminopeptidase regµLator antibody; VEGF-induced aminopeptidase antibody Product Type:Polyclonal Antibody Immunogen Species:Homo sapiens () UniProt ID:Q9NZ08 Immunogen:SyntheQuantityd peptide derived from internal of ARTS-1. Raised in:Rabbit Reactivity:, Mouse, Rat Tested Applications:ELISA, WB; WB:1:500-1:3000 Background:Aminopeptidase that plays a central role in peptide trimming, a step required for the generation of most HLA class I-binding peptides. Peptide trimming is essential to customize longer precursor peptides to fit them to the correct length required for presentation on MHC class I molecµLes. Strongly prefers substrates 9-16 residues long. Rapidly degrades 13-mer to a 9-mer and then stops. Preferentially hydrolyzes the residue Leu and peptides with a hydrophobic C-terminus, while it has weak activity toward peptides with charged C-terminus. May play a role in the inactivation of peptide hormones. May be involved in the regµLation of blood pressure throµgh the inactivation of angiotensin II and/or the generation of bradykinin in the kidney. Hattori A., J. Biochem. 130:235-241(2001). Nakajima D., DNA Res. 9:99-106(2002). Clark H.F., Genome Res. 13:2265-2270(2003). Clonality:Polyclonal Isotype:IgG Purification Method:The antibody was affinity-purified from rabbit antiserum by affinity-chromatography using epitope-specific immunogen. Conjµgate:Non-conjµgated Buffer:Rabbit IgG in phosphate buffered saline (without Mg2+ and Ca2+), pH 7.4, 150mM NaCl, 0.02% sodium azide and 50% glycerol. Form:liquid Stroage:Upon receipt, store at -20°C or -80°C. Avoid repeated freeze. Target Names:ERAP1 Research Areas:CardiovascµLar?Cell biology;Immunology