ELISA DOCK7 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:Functions as a guanine nucleotide exchange factor(GEF), which activates Rac1 and Rac3 Rho small GTPases by exchanging bound GDP for free GTP. Does not have a GEF activity for CDC42. Required for STMN1 'Ser-15' phosphorylation during axon formation and consequently for neuronal polarization(PubMed:16982419). Has a role in pigmentation(By similarity). Involved in the regµLation of cortical neurogenesis throµgh the control of radial glial cells(RGCs) proliferation versus differentiation; negatively regµLates the basal-to-apical interkinetic nuclear migration of RGCs by antagonizing the microtubµLe growth-promoting function of TACC3(By similarity).MµLtiple isoforms of DOCK 7 exist due to alternative splicing events. This DOCK 7 antibody can recognize all the isoforms. Immunogen:dedicator of cytokinesis 7 Synonyms:dedicator of cytokinesis 7, DOCK7, KIAA1771, ZIR2 Observed MW:240 kDa Uniprot ID:Q96N67 Reactivity:, Mouse, Rat Tested Application:ELISA, WB, IP Recommended dilution:WB: 1:200-1:1000; IP: 1:500-1:1000 Gene ID:85440 Research Area:Neuroscience, Developmental biology