ELISA HACE1 anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3,-20? for 12 months(Avoid repeated freeze / thaw cycles.) Background:E3 ubiquitin-protein ligase involved in Golgi membrane fusion and regµLation of small GTPases. Acts as a regµLator of Golgi membrane dynamics during the cell cycle: recruited to Golgi membrane by Rab proteins and regµLates postmitotic Golgi membrane fusion. Acts by mediating ubiquitination during mitotic Golgi disassembly, ubiquitination serving as a signal for Golgi reassembly later, after cell division. Specifically interacts with GTP-bound RAC1, mediating ubiquitination and subsequent degradation of active RAC1, thereby playing a role in host defense against pathogens. May also act as a transcription regµLator via its interaction with RARB. Immunogen:HECT domain and ankyrin repeat containing, E3 ubiquitin protein ligase 1 Synonyms:KIAA1320 Observed MW:78 kDa Uniprot ID:Q8IYU2 Reactivity: Tested Application:ELISA, WB, IF Recommended dilution:WB: 1:500-1:2000; IF: 1:20-1:200 Gene ID:57531 Research Area:Epigenetics, Metabolism