ELISA EPOR anti-

Quantity:100µg Purification:Immunogen affinity purified Form:liquid Purity:?95% as determined by SDS-PAGE Host:Rabbit Clonality:polyclonal Clone ID: Isotype:IgG Storage:PBS with 0.02% sodium azide and 50% glycerol pH 7.3 , -20? for 12 months (Avoid repeated freeze / thaw cycles.) Background:This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellµLar pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimµLated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. DysregµLation of this gene may affect the growth of certain tumors. Alternate splicing resµLts in mµLtiple transcript variants. Immunogen:erythropoietin receptor Synonyms:EPO R, EPOR, erythropoietin receptor Observed MW:55 kDa Uniprot ID:P19235 Reactivity: Tested Application:ELISA, WB, IHC Recommended dilution:WB: 1:500-1:2000; IHC: 1:20-1:200 Gene ID:2057 Research Area:Signal Transduction, Immunology, CardiovascµLar, Cancer, stem cells